Sentence examples for binding chains in the from inspiring English sources

Previous studies have shown that hTLR2 can accommodate two ester bound lipid chains [31] and hTLR10 was found to possess amide bound lipid binding chains in the current study, which indicates that the tri-acylated (Pam3CSK4) lipopeptides act as ligand molecules.

But withefrin A disrupts majority of these hydrophobic interactions by placing itself in between the binding chains, As depicted in Figure 6 for Cluster 1, WA itself starts forming strong intermolecular interactions with these critical residues.

This is likely due to the z peptide of cp-MVP-z vaults binding antibody heavy chains in the media.

Since the receptor-binding region is distinct from the binding site for GAG chains in the extracellular matrix, it is possible that the anti-VEGF binds to matrix-bound VEGF.

According to Istvan et al.[17] the orientation of the side chains in the binding sites does not differ among the statins.

Biochemical assays on both PepTSt and GkPOT have been reported that also provide additional clues as to the function of conserved side chains in the binding site.

Notably, Qamar and co-workers [ 49] suggested a potential role of the fatty acyl chains in the binding of autoantibodies to lysophosphatidylethanolamine.

The ligands were docked to the 3HVL chain A using semiflexible docking whereby the ligand has full conformational flexibility and the hydroxyl groups of designated protein side chains in the binding pocket can rotate to optimize hydrogen bond contacts.

These spatial arrangements of FA and the side chains in the binding pocket were similarly observed at room temperature, at which the C12 C18 portion of the FAs became disordered as compared with the structures at low temperature.

These results are consistent with our earlier report that, as a Smt3 binding protein, Zip1 protects Smt3 chains in the zip3Δ mutant through competition with Ulp2 (Cheng et al, 2006).

An alternative possibility is that the replacement of the Met68 with Val reduces the packing of the hydrophobic side chains in the binding site, and this in turn promotes the open conformation observed in the structure of the wild-type YdiI·(UDO-CoA) complex.