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The diol binding capacity and selectivity of the phenylboronic acid remain unchanged after anchoring to polymer nanoparticles (16 nm diameter, 0.22 mmol/g).
MIPs synthesized at different conditions, which displayed different properties (binding capacity and selectivity), and respective non-imprinted polymers were employed for the fabrication of the potentiometric sensors.
Influence of the synthesis conditions, namely monomer/template ratio and reaction duration, on the polymer binding capacity and selectivity towards aromatic compounds was investigated.
Three lead ligands were identified due to their superior performance in terms of binding capacity and selectivity towards the phosphorylated moiety on peptides, which showed the feasibility of the Petasis-Ugi reaction for affinity ligand development.
The lead candidate (coined A8A3), composed of histidine and phenylalanine mimetic components, showed high binding capacity and selectivity for binding mono- and multi-phosphorylated peptides at pH 3. Ligand A8A3 was coupled onto both cross-linked agarose and magnetic nanoparticles, presenting higher binding capacities (100-fold higher) when immobilized on the magnetic support.
Therefore, the binding capacity and selectivity of the composite would be improved with a greater attached amount of MEL-A.
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It was found that the hydrogen bond interaction between anions of the ILs and acidic proton of the functional monomer was the main driving force for the high adsorption selectivity of the imprinted polymers, and the stronger hydrogen bond interaction indicates higher binding capacity and higher selectivity of the polymers towards the ILs.
Thus, eIF4E binding capacity and cytotoxic activity are tightly linked.
Mesophyll effects are characterized as a product of CO2 binding capacity and the electron transport capacity.
The main strengths of the concept are that a small set of polypeptides can be used to develop binder molecules for any protein by conjugation to small molecules or peptides with only modest binding capacities, and that the binder molecules target the proteins that the small molecules recognise but with much improved affinity and selectivity.
Examples such as MIP-based selective analysis of flavones/flavonoids in wine, the determination of mycotoxins in beverages and analysis of organic contaminants in environment samples will elucidate the perspectives of this technology and will be contrasted with the challenges of rational MIP design providing control on binding site density, receptor capacity and selectivity.
More suggestions(15)
binding capacity and efficiency
binding ability and selectivity
binding capacity and magnetism
binding capacity and expression
binding capacity and affinity
binding efficiency and selectivity
binding capacity and dissociation
binding capacity and signal
binding activity and selectivity
binding capacity and binding
binding affinity and selectivity
binding potency and selectivity
binding capacity and outcome
binding capacity and control
binding capacity and ability
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