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The antigen binding capability of the bioconjugates was confirmed by ELISA.
Here, using low molar ratios (1 1 to 1 100) of the two linkers resulted in loss of binding capability of the anti-EGFR (epidermal growth factor receptor) antibody nimotuzumab, as assessed by surface plasmon resonance imaging.
or largely reduce (KD = 32 and 120 μM, respectively) the binding capability of the two peptides, suggesting that these PR residues could be the potential target sites for developing resistance-free anti-HIV agents.
Immunoprecipitation studies indicate that the LC of BoNT/A ad forms a complex with SNAP25 present in the neuronal cytosolic fraction, demonstrating that the atoxic LC retains the SNAP25 binding capability of the wt toxin.
In EMSA studies we tested for the DNA binding capability of the two mutated transcription factors.
Also, the electro negative groups (-Br, -I) of the designed molecules forms intermolecular bumps which disfavors the binding capability of the molecules.
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The binding capability of these cationic polymers to the siRNA molecule, subsequently controls the surface/adsorption behaviour of the complexes to a negatively charged surface.
The design of selective inhibitors is hindered due to the broad substrate binding capabilities of the GST enzymes.
ELISA was used to test the binding capabilities of the three constructs to Diva.
Carbohydrate-binding assay directly confirmed the binding capabilities of the N-and C-terminal domains.
The glycan binding capabilities of the purified GRFT were determined through gp120 binding.
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