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These results suggest that Sec61β may interact with microtubules and the binding can be prevented with a large tag at the N-terminus.
However, by introducing two PEG [poly ethylene glycol)] moieties, TRC40 binding can be prevented, resulting in a block of subsequent membrane integration.
This binding can be prevented by the interaction with CsrB or CsrC that consist of several CsrA binding sites and sequester this protein [ 212].
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The vacuum tests also showed that evaporation or freezing of the binding liquid can be prevented through a proper injection method.
Alternatively, growth factor binding to the receptor can be prevented by expression of a mutant growth factor, or by sequestering the growth factor extracellularly.
It has previously been shown that SOS can be prevented from binding to Ras by an autoinhibitory mechanism, in which the Ras binding site on the catalytic domain of SOS is blocked by another portion of the SOS protein.
We have recently shown that C1q can be prevented from binding to polystyrene surfaces conjugated with CS-A and to the surface of activated platelets by soluble CS-A at very high concentrations (50 mg/mL) [15].
We also showed that in AC16 cells amyloidogenic TTR-induced cytotoxicity can be prevented by kinetically stabilizing the native tetramer with small molecules that bind in the TTR T4 binding pocket preventing its dissociation and the ensuing amyloidogenic cascade.
Corrosion can be prevented in two ways.
Hepatitis B can be prevented through vaccination.
Thus, data collision can be prevented.
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