Sentence examples for binding calcium from inspiring English sources

In addition to binding calcium and heparin glycosaminoglycan chains, OMM-64 binds Otolin.

Interference in the metabolism of vitamin K in the liver by coumarin derivatives gives rise to clotting factors that are defective and incapable of binding calcium ions (another important element in the activation of coagulation factors at several steps in the coagulation cascade).

In the molecular function (MF) category, based on the counts of enriched genes, Table 1 shows the top 20 terms involved in multiple functions such as nucleoside binding, ATP binding, RNA binding, calcium ion binding, and enzyme binding.

Using small-angle x-ray scattering and NMR spectroscopy, we show that TN-XXL changes from a flexible elongated to a rigid globular shape upon binding calcium, thus resulting in FRET signal output.

The two charged amino acid rings of Glu-Glu-Asp-Asp (EEDD) and Asp-Glu-Lys-Ala (DEKA) around the selectivity filter region are seen to play a crucial role in making the channel sodium selective, and strongly binding calcium ions such that they block the channel.

Thyrotropin-releasing hormone (TRH) analogues bearing halogen groups (Cl, Br and I) at the C-2 and/or C-5 position, and the alkyl group (CH3, C2H5, C3H7, CH2C6H5) at the N-1 position of the imidazole ring of the central histidine residue were synthesized and evaluated for the receptor binding, calcium mobilization (FLIPR), and IP-1 assay at the HEK mTRHR1 and HEK mTRHR2 expressing cell lines.

Differentially expressed miRNAs were further analyzed for their putative target genes using TargetScan and were listed in the table 2. Most of the target genes(>1400 genes) have molecular function of metal ion binding, calcium-potassium-chloride ion binding, correlated to the restructuring heart after IR damage.

In negatively gravitropic (upward bending) protonemata, the statoliths-induced drastic upward shift of the cell tip is preceded by a relocalization of dihydropyridine-binding calcium channels and of the apical calcium gradient to the upper flank (bending by bulging).

P2RX7 is a purinergic ATP-binding calcium channel expressed in microglial cells and considered a candidate gene in type I diabetes [ 50].

In addition, some of the predicted targets were annotated as being involved in various classes of molecular functions, including binding proteins (DNA-binding, RNA-binding, ATP-binding and protein-binding), calcium ion transport proteins, and enzymes (protein kinase, synthetase/ligase, acetate-CoA ligase, glycoside hydrolase and oxidoreductase).

Similarly, over-represented molecular functions included actin-binding (GO 0003779), calcium ion binding (GO 0005509) and phospholipid binding (GO 0005543).