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Some conservative elements within the Church have disputed that Nostra Aetate is binding because it is "merely" a decree, not a constitution or a declaration.
For centuries, Chinese women were oppressed with the tradition of feet binding, because it was believed that smaller the were, the better – a cruelty described most famously in Jung Chang's Wild Swans.
However, under current Spanish law, the referendum would not be binding because it has not received the backing of the central government.
We therefore conclude that the DCC short isoform shows reduced netrin-1 binding, because it cannot use all possible combinations of the three DCC binding sites present on netrin-1.
ER regulation is not limited to direct ligand binding, because it can also be modulated by several other pathways.
Zip1C3N−3R is incompetent in Smt3 binding because it has three point mutations (E862R, D863R and Q864R) in the SIM (residues 853 864) (Cheng et al, 2006).
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This β-Gal binding site is conserved among all BV, NV, FUV and TCH with known crystal structures (Bu et al., 2008; Choi et al., 2008; Kubota et al., 2012; Shanker et al., 2014) and thus may be defined as the central binding pocket (CBP) of GI HBGA binding interfaces, because it plays the central role in GI NoV-HBGA interactions, as proposed previously (Tan and Jiang, 2014).
Isothermal titration calorimetry (ITC) is uniquely useful for characterizing binding thermodynamics, because it straightforwardly provides both the binding enthalpy and free energy.
Finally, cluster 5 is identified as the preferred binding site because it has the lowest mean binding energy and the largest number of structures.
The predominant assay type is termed "type-B" or binding assay because it encompasses the enzyme inhibition and receptor binding assays most commonly reported for compounds tested against molecular targets in vitro and, implicitly, with binding specificity.
Nevertheless, the D. melanogaster PAM2 motif contributes to PABPC1 binding, because when it is deleted from a protein lacking the C-term region, PABPC1-binding efficiency decreases further.
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