Sentence examples for binding avidity that was from inspiring English sources
By measuring the relative avidity of anti-Hcβtre serum Ig with the use of a modified ELISA [29] [31] that tests serum at similar antibody concentrations, we determined that serum samples with BoNT/A neutralization activity exhibited a relative binding avidity that was significantly higher than the relative avidity of non-neutralizing antibodies.
BRDs are often associated with other protein-interaction modules, a mechanism that is thought to generate high target selectivity and increased binding affinity with substrates owing to avidity that is generated on simultaneous binding of several interaction domains.
These two setups allow us to obtain data on the individual binding affinity as well as the avidity that is inherently linked to the dimeric nature of the ligands.
As such, even though the genetic change is one and the same, the change in binding avidity that results can be thought of as increasing the background fitness of a virus strain, whereas the change in antigenicity that results can be considered as in this paper.
This raises a paradox in the context of the NPC, because multivalent interactions are generally known to impart strong binding avidity that enhances stability and specificity.
We established a VZV avidity assay that is suitable for comparative evaluation of antibody avidity in serum and CSF samples.
An increase in avidity in the individuals that were avidity tested both in 1994 and 1999 supports this idea.
One such finding is that cellular receptor binding avidity is an important phenotype that impacts viral fitness (Hensley et al., 2009).
Nevertheless, it was reported that multivalent binding avidity can be kinetically limited if the binding affinity of an individual receptor-ligand pair is too tight [44, 45].
As a result, the on-rate for the second binding is very high (typical avidity effects show an on rate that is 100 times or more larger than the first binding rate [ 4, 22]).
In addition, IgG avidity test is an important additional test that is routinely performed; with low IgG avidity suggesting acute infection while high IgG avidity confirms chronic infection [ 9].
