Sentence examples for binding avidity plays a from inspiring English sources

Indeed, the integral binding avidity plays a predominant role in the targeting efficacy; the higher integral binding avidity increases the targeting efficacy.

We did not mean to imply that there is necessarily one discrete binding mode but rather believe that avidity plays a significant role in complex assembly, using multiple binding modes that engage different flexible NESs and possibly different forms of the Rev oligomer.

Furthermore, we found that antibody binding valence also plays a critical role in mediating the viral neutralization through a mechanism that is likely unrelated to antibody size or binding avidity.

The binding avidity of NLP-A to P. brassicae spores was comparable to that of a polyclonal antibody.

In contrast, an AAV9 mutant with decreased glycan binding avidity displayed a liver-detargeted phenotype.

We also show that multiples of cyclic peptides further increase the period of retention of cytokine in the target tissue, most likely through increased binding avidity, thus providing a strategy for overcoming the general low affinity binding properties of peptides.

One such finding is that cellular receptor binding avidity is an important phenotype that impacts viral fitness (Hensley et al., 2009).

TF-DNA binding avidity: an integrative quantitative characteristic of availability of a DNA locus (e.g. TFBS and its flanking region) for a given protein (e.g. TF) binding Sp: specificity Se: sensitivity: (1- p0)100%.

In addition to directing multi-partite interactions with high specificity and avidity, motif co-operativity also plays a fundamental role in cellular decision-making.

Although multivalency plays a role in increasing avidity of interactions of many glycan-binding receptors, for the mannose-binding protein the geometry of the placement of multiple binding sites facing a single direction is a determining feature for broad recognition of glycan-rich surfaces without requiring specific complex oligosaccharide structures (Weis and Drickamer 1994).

Recombinant antibody fragments can be engineered to assemble into stable multimeric oligomers of high binding avidity and specificity to a wide range of target antigens and haptens.