Sentence examples for binding at these regions from inspiring English sources

Further analysis highlighted that the loss of these putative SP1-binding sites is also associated with detectable falls in the observed levels of SP1 binding at these regions (fig. 3 A).

Reduction of H3K9me3 levels through down-regulation of methyltransferases Suv39H1&2 enhances Oct4 and Sox2 binding at these regions and increases reprogramming efficiency (Onder et al, 2012; Soufi et al, 2012).

As cell-line specific CTCF binding events are more likely to overlap with cell-line specific ER binding events, CTCF may direct ER binding at these regions thereby acting as a 'licensing factor' for ER.

However, the normalised sum of the intensities of CTCF, ER and FOXA1 binding, in regions co-bound by all three factors, was 190, 782, 252, 928 and 137, 374, respectively, showing that ER binding intensity at these regions is not weaker than CTCF binding.

Given the enrichment of CTCF and Smc1 protein binding sites at these regions, it is possible that such stable contacts may be mediated by these proteins.

We then targeted nine regions that we experimentally determined were bound by both C/EBPβ and ZEB1 as well as the sole ZEB1-only bound region to determine the ZEB1 DNA binding enrichment at these regions in stable C/EBPβ knockdown versus control cells using ZEB1 ChIP-qPCR.

BRG1 is known to bind to both promoters and distal sites11 and further analysis of BRD9 and ARID1A binding at these different regions showed that the two have different binding proclivities, with BRD9 binding more strongly to promoters and ARID1A more strongly to distal sites (Fig. 3e).

Together these results show that Swi6 dynamics in heterochromatin do not differ significantly at centromeres compared with telomeres and respond equally to RNA binding at these heterochromatin regions.

Like other TFs, OmpR may prevent binding of other repressors or directly activate transcription by recruiting RNAP, or exclude RNAP binding at this region to repress transcription.

First, we confirmed that Meis binding is increased at these regions in the IIBA.

Both the amino and the carboxyl ends of the molecule vary in their charge distribution depending on pH, and a single binding pocket directed at these regions would not offer sufficient affinity under all conditions.