Sentence examples for binding at the promoter from inspiring English sources

Physical binding at the promoter is a crucial evidence for a transcription factor to regulate transcription of a gene directly in yeast.

In order to investigate the effect of Compound A on ERRα binding at the promoter region of ERRα target genes (ESRRA, ACADM, and TFF1), chromatin Immunoprecipitation (ChIP) assays were performed after MCF-7 cells were treated with DMSO, 3 pM 17β-estradiol (E2), or 5 uM Compound A for 24 and 48 hours.

Thus, increasing the RNA polymerase (RNAP) binding at the promoter site would effectively activate transcription of the target genes.

Loss of binding at the promoter, or the body of the gene, or both was detected on other loci.

Rather than simply transcription factor binding at the promoter, active initiation by RNAP II is important for MEL development (Wilcox test p < 0.005 for all groups; Figure 3E).

Moreover, chromatin immunoprecipitation (ChIP) results showed that overexpression of PANDAR could detect a loss of NF-YA binding at the promoter of Bcl-2.

In addition, we observed low levels of NdgR binding at the promoters of metH (SCO1657) and leuA (SCO5559) relative to the other binding peaks.

Notwithstanding its direct binding at the promoters of genes in the BCAA biosynthetic pathway, NdgR was not essential for BCAA biosynthesis under the growth conditions used here.

(A – B ) IGV images of ChIP-seq data revealing high infection-dependent WRKY33 binding at the promoters of AMT1 (A ) and CYP71A12 (B ).

(B, C ) Integrative Genomics Viewer (IGV) images of ChIP-seq data revealing high infection-dependent WRKY33 binding at the promoters of Arabidopsis WRKY33 (B ) and WRKY41 (C ).

Twenty-four hours after KSHV reactivation, we found a significant increase in SUMO-2/3 binding at the promoters of genes with high expression (~15%) and medium expression (~10%).