The miRNA sequence is complementary to the 3′ untranslated region (UTR) of its target mRNA, and the resulting complementary binding inhibits gene expression at the post-transcriptional level by mediating mRNA breakdown or translation inhibition.
This post-translational modification appears to modulate MeCP2 binding at the BDNF promoter in the hippocampus.
A young mother at the post agrees.
Check it out at the post office.
The pre- or post-attachment neutralization assay and syncytium formation inhibition assay revealed that m27f neutralizes HSV at the post-binding stage.
While the role of DNA-binding proteins, particularly transcription factors, in regulating gene expression at the level of transcription has received much attention, how RNA-binding proteins control gene expression at the post-transcriptional level remains unclear.
Compared to TFs, expression alteration of RNA-binding proteins (RBPs), master regulators at the post-transcriptional level, was less studied but deregulated transcriptions of several RBPs also have been reported to play a critical role in human cancers [ 9- 12].
RNA-binding proteins govern gene regulatory events at the post-transcriptional level.
