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At the higher dose that saturated PIP2 binding at the plasma membrane, the PH fusion protein also had an effect on the structure of the subplasmalemmal actin cytoskeleton, and significantly altered the dynamics of Ca2+ signaling inside the egg.
Related to Figure 7 Model of AP2 activation and cargo binding at the plasma membrane.
Upon ligand binding at the plasma membrane, signaling events mediated by the IGF-1R occurs primarily through activation of PI3K-Akt and MAPK pathways [ 40].
The use of specific receptors to obtain growth factors or nutrients ensures temporal prolongation of signal transduction initiated upon ligand binding at the plasma membrane and continued after internalization.
More specifically, for cells expressing myrGag CFP and myrGag YFP we expect almost no Gag protein binding at the plasma membrane and so this acts as a biological control for negligible FRET (columns 1 and 2 of Figure 6 c).
A spatial selectivity of SUMO-2 to PI 3,4,5 P3 binding at the plasma membrane may be caused by differences in the cholesterol to phospholipid ratio which is higher in the plasma membrane compared to endosomal membranes [ 72].
Similar(51)
When DES was added at the same time as E-HRP, it decreased the binding of E-HRP to its binding site at the plasma membrane, producing a reduced amount of precipitate.
In both trypanosomatids the metal ion is acquired by endocytosis, following its binding to Tf which has a receptor (or binding protein) at the plasma membrane [14], [41], [42].
To further demonstrate the implication of a membrane binding site, we used a binding assay method based on the interaction of E-HRP as a specific probe to detect E2 binding sites at the plasma membrane of nonpermeabilized cells.
This finding is in agreement with a NPA binding activity at the plasma membrane [ 46].
NHERF1 is a PDZ-domain adapter protein that stabilizes its binding partners at the plasma membrane.
More suggestions(15)
binding at the lineout
binding at the frq
binding at the fru
binding at the canyon
binding at the time
binding at the expense
binding at the promoter
binding at the cell
binding at the surface
binding at the site
binding at the tip
binding at the assembly
binding at the end
binding at the membrane
binding at the octamer
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