Sentence examples for binding at the pho1 from inspiring English sources

Pho7 binding at the pho1 + promoter in a csk1Δ background is mildly increased compared to a csk1 + background.

This increase in binding is less than the observed increase in Pho7 binding in csk1 + cells grown in no- vs. high-Pi conditions (1.2-fold versus 4-fold), suggesting that Csk1 is not the major regulator of Pho7 binding at the pho1 + promoter.

One reference compound (C64) was extensively characterized for selective binding at the RBX1-binding grooves/VLYRLWLN of CUL1-7.

Molecular modeling studies suggest that 5-thiomethylthiopheneamidine inhibits uPA by binding at the S1 pocket of the active site.

A series of xanomeline analogs were synthesized and evaluated for binding at the M1 muscarinic acetylcholine receptor (M1 receptor).

Protein binding at the DNMT3A tetramerization interface is important for methylation patterning, inducing processive methylation of clustered sites (Jia et al., 2007).

Mg-ATP binding at the NBD2 consensus site can have similar functions as Mg-ADP, albeit with lower affinity (Vedovato et al., 2015).

These results indicate that the catechol fragment is critical for the D2 receptor binding of the anti-parkinsonian drug, APO -1), but not necessary for binding at the D1 and 5-HT1A receptors.

This mechanism likely explains the reported ability of BRD7 to inhibit cell cycle progression from G1 to S phase, though direct binding at the E2F3 promoter may also facilitate this (Peng et al., 2006).

Mechanistically, glycolysis might promote IFN-γ production by inducing GAPDH activation and releasing GAPDH from binding at the 3′UTR of the IFN-γ promoter, thereby inducing IFN-γ production via post- transciptional mechanisms [19].

Based on this scaffold, we designed inhibitors for efficient binding at the L5 site in CENP-E utilizing homology modeling as well as electrostatic potential map (EPM) analysis to enhance CENP-E inhibitory activity.