Sentence examples for binding at the C-terminus from inspiring English sources

Methionine (M) and Tryptophane (W) are strongly preferred residues for binding at the C-terminus of murine TAP, while they have little or no effect for human TAP.

Amino acid motifs responsible for citrate binding at the C-terminus are characterized by two basic residues and one acidic residue that apparently enable strong allosteric effects of the ligand on the protein.

KIF1C may attach to membranes via Rab6A binding at the C-terminus.

This complexity arises in part from many observations suggesting that CFTR is part of a multimolecular complex in the apical membrane of epithelial cells containing (besides protein kinases) N-terminal inhibitory syntaxins, PKA-interacting ezrin binding phosphoprotein (6), and many others including CAP 70 (7) and more recently a cAMP-efflux pump binding at the C-terminus of CFTR (8).

Since mutations in the C. elegans ortholog of Mint2 (lin-10) cause defects in the clustering of the AMPA-type glutamate receptor subunit GLR-1 at the synapses of ventral cord interneurons and LIN-10 can bind to the PDZ binding motif at the C-terminus of GLR-1 [22], we hypothesized that CASY-1 might regulate the synaptic function or transport of GLR-1.

Poly(A) binding protein (PABP) which potentially binds at the C-terminus of TNRC6 was shown to bind directly to tumor susceptibility gene 101 (thereby thereby providing the link between the RISC complex and exosomes (Schlundt et al., 2009).

The RIG-I protein is comprised of four major domain groups including the caspase activation and recruitment domains (CARDs) (black), and RNA-stimulated ATPase core (green), a helical regulatory and binding domain inserted into the second lobe of the ATPase called HEL2i (cyan), and a triphosphate recognition and RNA binding domain at the c-terminus annotated the C-terminal domain (CTD) (orange).

We predict that this particular allele of Salmon class I molecule might have a very similar binding motif at the C-terminus compared with a known mouse class I molecule H2-Kb which has L, or I, V, M at p8.

The toxins are single chain proteins of an A/B type structure where the catalytic active glucosyltransferase domain is located at the N-terminus and the proposed receptor binding domain at the C-terminus [2].

Analyses of citrate binding sites on the PFK1 enzymes of various eukaryotic organisms revealed that identical amino acid residues were found at the N-terminus in all examined species (Fig. 1A); however, more variance was observed among the binding sites at the C-terminus.

These isoforms differ by the presence or absence of two N-terminal inserts (exon 2 and/or 3 inclusion) and the presence of either three or four imperfect repeats (3R or 4R) in the microtubule binding domain at the C-terminus (exon 10 inclusion) [2], [6] [8].