Sentence examples for binding at low concentrations from inspiring English sources

In contrast, the wild-type UBA monomer underwent significant perturbations (many > 0.2 ppm, as reported [24]) demonstrating strong binding at low concentrations of protein.

The rapid speed, small sample volume and ability to measure binding at low concentrations have led FCS to be proposed as an alternative to ELISA for the measurement of serum biomarkers [ 3].

However, these data are not greatly informative for TCE exposure in which DCA levels are significantly lower, and limitation to a single concentration precludes fitting to standard binding equations from which the binding at low concentrations could be extrapolated.

This could be explained by passive transfer of lead into breast milk driven by high affinity compartment in milk, thus allowing binding at low concentrations and drawing lead into milk.

Since the kcat/ Km is essentially a second-order rate constant for ligand binding at low concentrations, this result is consistent with these residues potentially being involved with activation of the enzyme.

The hypothesis is that spermidine can block the action of PCR inhibitors (possibly by binding them and or making them more thermolabile, or, alternatively, that by binding DNA at low concentrations it can drastically decrease the action of the PCR inhibitors).

This was supported using MI-43 (another compound that disrupted Mdm2-p53 binding) which at low concentrations induced remarkable induction of p53 leading to 90% cells arrested of A549 cells at the G1 phase without apparent apoptosis, although Puma and Noxa were also induced.

The hermetic dose response relationship for androgens is theorized to result from receptor binding-activation at low concentrations and chromatin rearrangement-quiescence at high concentrations.

Features associated with single molecule binding events dominate at low concentrations.

However, antibodies capable of efficiently binding the analyte at low concentrations are required for the IMS step to become useful.

While it appears that Oto and Wnt3a bind directly, other linking proteins or binding partners may be present at low concentrations, and although we think it unlikely, it is possible that minor residual disulfide bridges and/or protein denaturation may contribute to the observed Oto/Wnt association.