Sentence examples for binding at distal sites from inspiring English sources

In others the effects are exerted by binding at distal sites that rely on flexibility within the protein's architecture to communicate binding site occupancy to the catalytic center.

These deformations are frequently used to alter binding at distal sites, that is, allosteric regulation.

Yet, several marks and protein factor binding sites that are not associated with gene bodies also display higher H3.3-nucleosome turnover at distal sites compared to nucleosomes at proximal sites.

We did find virus at distal sites as early as four hours pi.

Its expression level increases 935.76-fold from GCB to ABC FDRR = 6.45 × 10−16) and is associated with increased STAT3 binding at a distal site about 27 kb downstream (FDR = 1.33 × 10−19).

A similar effect might be associated with substitution of the invariant Tyr702, which is located within the REM domain at the interface with the CDC25 domain, in close proximity to the region of the latter that undergoes the conformational switch promoted by RAS binding at the distal site.

HDAC1 binding does not significantly change, but acetyl-HDAC1 binding increased at the distal site.

MOF was not enriched at super enhancers and generally, its binding to TSS-distal sites was much less pronounced than to gene promoters.

H3.3 dissociation rates on the other hand, are significantly higher at distal binding sites.

Ectopically overexpressed FOXO3a or combined treatment with doxorubicin to induce FOXO3a nuclear accumulation leads to further binding at the distal FOXO3a site (-249 ~ -242).

These data demonstrate that binding of dTCF to the distal sites is necessary to inhibit dpp transcription.