Sentence examples for binding at a site from inspiring English sources

As a consequence, binding at a site of target up-regulation can be rapid, a property that would be valuable in the context of a clinical contrast agent.

In addition we reported that polyphosphates such as ATP and triphosphate act as non-substrate heterotrophic activators, binding at a site distinct from the active site and distinct from the peptide activation site [12].

Our docking analyses also explain the inability of CTP to serve as a phosphoryl donor to DCoA as it shows specific and stoichiometric binding at a site distinct from that of ATP (the P-loop).

This work establishes that the initial activation by phenylalanine involves binding at a site other than the active site.

The results of the experiments described here strongly support a model in which activation of PheH by phenylalanine involves binding at a site other than the active site.

The TPIMS inhibitors did not prevent binding of As III), indicating noncompetitive binding at a site distinct from the substrate binding site.

Further, it has been demonstrated that the agent blocks protein synthesis by competing with the amino acid side chains of incoming aminoacyl-tRNAs for binding at the A-site of formed ribosomes [ 81].

This is likely to be realistic in many cases, as we would not expect the existence of a weak binding site to adversely affect transcription factor binding at a stronger site.

Instead, Zn II) suppresses the formation of the tetramer, which implies its binding occurs at a site that interferes with tetramer formation.

5 Nonnucleoside/nucleotide reverse transcriptase inhibitors block reverse transcriptase by binding at a different site on the enzyme than NRTIs.

This is where a DNA-binding protein is immunoprecipitated with its cognate DNA and the presence of DNA binding at a specific site is assessed by quantitative PCR.