Sentence examples for binding assay could be from inspiring English sources

The new binding assay could be used to determine the KD of other PBPs.

An in vitro FcRn binding assay could be a highly valuable complementary tool to assess IgG antibody pharmacokinetics in IgG engineering and screening during the early optimization stage.

Moreover, these data showing a correlation between cytotoxicity and Topo I inhibition or DNA binding capacity are very important as they strongly suggested that the Topo I-mediated DNA cleavage assay and DNA binding assay could be used as a guide to design and develop superior analogues for antitumor activities.

The apparent discrepancy between the in vivo and in vitro binding assays could be due to different folding of the protein under the two different conditions, suggesting that the Y15A, K186Q, or LL241 242AA mutations might affect the conformation or the higher-order structure of HIV-1 IN that is required for efficient interaction with SIP1 in vivo.

This means that while in general competitive binding assays could be developed with any kinase of interest, a single probe cannot be used for all (or even most) kinases, and new probes will need to be developed in order to access different subsets of targets.

Limited exploration by new analog synthesis showed that the binding inhibition in a FRET assay could be improved to the low μM level making this new core a potential hit-to-lead series.

In vitro methods, such as high-throughput aryl hydrocarbon receptor binding assays or the CALUX® assay, could be used as screening tools.

In conclusion, the LAL assay could be successfully used to test supernatants of endotoxin binding studies in aqueous solution and artificial intestinal fluid.

The selectivity of class 2 docking interactions, demonstrated in binding and biochemical assays, could be altered by mutagenesis.

Using binding assays, it could be demonstrated that PANC-1 pancreatic cancer cells express high numbers of specific IL-4 binding sites (Kawakami et al, 2002).

Nonetheless, HNF4α DNA binding activity could be assayed for in EMSA supershift assays and was significantly reduced to 58% after treatment with 8.3 µM (10 µg/ml) cyclosporine (Fig. 3C, 3D).