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It was suggested that GAAGA might be a high-affinity binding site for factors that influence EJC binding; as such, it is possible that these proteins bind this motif to attract EJC factors during splicing and/or to stabilize the EJC in specific genes.
The antioxidant function of HK II relies on its mitochondrial binding as such, and is independent of its enzymatic activity.
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However, in silico predictions poorly correlate with in vivo transcription factor binding, and as such, this approach has limited ability to predict bona fide PPARγ binding.
Electrostatic interactions have been identified as one efficient mechanism for enhancing binding specificity; as such, the effects of charged and polar groups were the focus of this study.
These kits are based on competition for a cAMP binding site on an antibody or cAMP binding protein and as such have a limited dynamic range.
Since DVR represents equilibrium binding quantity and as such is independent of blood flow [ 9, 29].
S-oligos act as heparin mimetics and they bind to heparin binding proteins such as bFGF (Benimetskaya et al, 1995).
Since cholesterol is water insoluble, quantitatively very little unbound cholesterol is detected in cytosol, most of the cholesterol exists as protein binding form such as apoE containing cholesterol particle in cytosol.
Once RA is synthesized, it binds to cytosolic RA binding proteins (such as CRABP).
This technique yields binding information such as affinity and overall binding capacity as well as whether addition of AHLs impacts on the membrane organization.
These functions include different types of binding, such as ATP binding or RNA binding, and classes of activity, such as hydrolase activity or protein transporter activity.
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