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Despite the elimination of substrate binding as a rate-limiting step, the use of caged benzyl alcohol does not produce a measurable H/D kinetic isotope effect.
By clustering these proteins, β-arrestin eliminates RAF MEK binding as a rate-limiting step.
Similar(58)
As such, nuclear p120 acts as a rate-limiting antagonist of Kaiso-dependent transcriptional repression.
Adipose triglyceride lipase (ATGL) has been identified as a rate-limiting enzyme of mammalian triglyceride catabolism.
Thereby C-glucosylation was identified as a rate-limiting step at the applied conditions.
The first stage can be the binding of monomers to the membrane, as assumed here, or a rate-limiting nucleation step that triggers the oligomerization reaction, as assumed elsewhere (Hotze et al., 2001).
As stated above, this represents a rate-limiting step in the overall biosynthesis reaction.
The promoter of G6Pase, a rate-limiting enzyme for gluconeogenesis, contains binding sites of both CREB/CRTC2 (cAMP response element, CRE) and HDAC5/FOXO1 (insulin response element, IRE) (Lan et al., 2007; Liu et al., 2008).
Dopamine is classified as a catecholamine synthesized from tyrosine by TH, a rate-limiting enzyme.
This step is considered as a rate limiting step of taurine biosynthesis in animals.
Thus, the reduction of hyperoxidized Prx by Srx might be considered as a rate limiting step.
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