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QacR represses transcription of the qacA multidrug efflux transporter gene by binding as a pair of dimers to the IR1 DNA operator sequence, a large inverted repeat that overlaps the qacA promoter (PqacA) [9], [10].
Recent analysis of crystal structures of an R-spondin fragment and LGR5 ectodomain revealed the mode of binding as a pair of heterodimers.
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Based on the binding clusters identified in the two biological replicates, a consensus binding cluster was defined as a pair of clusters from the two replicates, if preferred crosslinking site of one cluster from one replicate was located within the other cluster from the other replicate and vice versa.
The other end of the adapter is comprised of single stranded, divergent sequences that serve as binding sites for a pair of primers that, after PCR, generate DNA fragments that have different adapter sequences on each end.
unbind_axes Removes the binding between a pair of axes.
unbind_axes axes Removes the binding between a pair of axes.
Removes the binding between a pair of axes.
The substrate binding model and MD simulation provide the molecular basis for the biochemical behaviors of the enzyme, including noncooperative substrate binding, indiscrimination of a pair of epimers as the substrates, proton wire switching during catalysis, and formation of epimerization product.
They came as a pair.
Jackie Chan and Snow Bunny played as a pair.
"We have developed as a pair.
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