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The more flumazenil added to the tracer solution, the fewer GABA receptors will be available for binding; as a consequence, the elimination from brain was faster.
An implication of those results was that chAbs might also manifest differences in Ag binding as a consequence of amino acid sequence dissimilarities between heterologous C regions.
NOX5 is regulated by calcium binding as a consequence of EF motifs in its N-terminal domain.
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28 Furthermore, similar to mevinolin, no changes are observed within the MIDAS binding site as a consequence of IBE-667 binding to LFA-1 ID.
This fluoresence was quenched after Evans blue (EB) inhibitor or HIV-1 gproteinotein binding, presumably as a consequence of changes in the distance and dipole orientation between the donor and acceptor; the emission intensity at 420 nm decreased in a concentration-dependent fashion.
Finally, Figure5 shows the variation of the heavy-hole exciton binding energy as a consequence of the increment in the intensity of the z-oriented applied dc electric field.
This suggests that these residues are actually involved in some way in the control of protein-protein binding and, as a consequence, in the control of the Sirt-1 function.
Furthermore, it is likely that DNA sequence differences, taken with the wider context of the regulated gene, may affect the on and off rates for GR binding, and as a consequence make some genes more critically dependent on ligand bound GR than others.
However, the size of the nucleosomes is significantly bigger than transcription factor binding sites, as a consequence the resulting configurations of nucleosomes can be more complex.
While WT Akt overexpression led to increased phospho-Akt levels (Ser473), this effect was not detected with the mutant isoform, possibly due to conformational changes in the antibody-binding site as a consequence of the mutation itself (Figure 3A).
We asked whether histone modifications facilitate TF binding or occur as a consequence of TF binding.
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