Sentence examples for binding are sufficient to from inspiring English sources

Thus the ATP switch model proposes that the conformational changes associated with ATP binding are sufficient to switch the substrate-binding site from high to low affinity, thus releasing the substrate on the other side of the membrane [ 54].

This binding was sufficient to reduce network excitability.

These results suggest that, 1) inhibition of polyubiquitin binding is sufficient to inhibit gp78-p97/VCP gp78-p97/VCP or 2) htt and antinteractionn antibory binding sterically blocks p97/VCP binding to its binding site [the p97/VCP-Interacting Motif (VIM)] in gp78 [52].

Based on our conclusion that Jak2 binding is sufficient to inhibit GHR endocytosis, we hypothesised that Jak2 must leave the GHR before the endocytosis machinery, including SCF βTrCP) and clathrin, can proceed [16].

This approximate ~ 10-fold increase in binding was sufficient to generate a complex suitable for crystallography.

This suggests that ORC binding is sufficient to determine a eukaryotic replication origin.

It appears that the alteration in bias of the G1Δnab constant region away from activatory receptor binding is sufficient to prevent destruction of these platelets.

We find that Arg-SH3SH2 binding is sufficient to activate N-WASp, or phospho-N-WASp, even in the absence of Cdc42.

The authors have found that ATP binding is sufficient to initiate a signaling response in the presence of an optimal RNA ligand.

We believe, however, that we have shown that the lack of NEDD4L binding is sufficient to explain the lack of function of AMOT p80.

In summary, these experiments demonstrate that the competition between hnRNP C and U2AF65 controls Alu exonization, and that weakening hnRNP C binding is sufficient to promote exon inclusion.