Sentence examples for binding are sensitive to from inspiring English sources

As Asf1 is a histone H3-H4 chaperone, some Asf1 mutants that influence histone binding are sensitive to agents that induce replicative stress or DNA damage [ 23].

We show that both association and dissociation rates of SRP binding are sensitive to active RNC translation, with rapid and stable SRP binding to RNCs only upon exposure of a signal sequence outside the ribosomal peptide tunnel.

CTCF binds to a set of signal sequences, with this binding being sensitive to methylation (Filippova, 2008), while also having the potential to mediate long-range chromosomal interactions (Ling et al., 2006).

Noriega, T.R. et al. Signal recognition particle-ribosome binding is sensitive to nascent chain length.

In broken cells mitochondrial binding was sensitive to a range of protease treatments.

CDK8 binding was sensitive to IKKβ inhibition and largely unperturbed by Stat1 deficiency.

Indeed, a previous study using the binding task found that the magnitude of binding was sensitive to the strength of the outcome prediction (Moore & Haggard, 2008).

In addition, we found that the binding is sensitive to imidazole and to pH values of ≤5.8, consistent with an essential role of histidine residues, which are protonated at lower pH and therefore incapable of coordinate bonding with the inhibitor.

These ionic interactions would explain why substrate binding is sensitive to substitutions at these charged positions [e.g., d-Trp, tryptamine, indole priopionic acid, and tryptophanol (Scheme 4)] and in some cases [e.g., tryptamine, indole propionic acid, and tryptophanol (Scheme 4)] essentially eliminates activity altogether.

These binding modes are sensitive to salt, temperature, pH, and binding density (Lohman and Ferrari, 1994).

Traditional analyses of binding rates, previously deduced from binding reactions using static, stalled RNCs, demonstrated that SRP-RNC binding kinetics are sensitive to nascent chain lengths but yielded conflicting results when describing SRP occupancy (Siegel and Walter, 1988; Bornemann et al., 2008; Holtkamp et al., 2012; Noriega et al., 2014).