Sentence examples for binding are required for from inspiring English sources
In light of these findings, we investigated whether both palmitoylation and receptor binding are required for hFasL raft localization.
Together, these results suggest that both deubiquitinase activity as well as HDAC6 binding are required for CYLD to regulate the cell cycle.
Given that CREB-DNA interactions do not change significantly at the majority (>99%) of sites in response to cAMP signaling, and that the co-activators CREBBP, EP300, and CRTC2 have no inherent sequence specificity, this result strongly supports the conclusion that other genomic features, in addition to the presence of CREB binding, are required for cAMP-responsive changes in gene expression.
Furthermore, these findings reveal that MLL not only "writes" the H3K4me3 mark but also binds the mark, and this binding is required for the transcriptional maintenance functions of MLL.
In this study, we sought to determine whether the yeast endocytic dynamin Vps1 was able to bind to actin and whether binding was required for all or just a subset of Vps1 functions in membrane trafficking.
Furthermore, neurabin binds to actin [76] and this binding is required for its localization in dendritic spines [39].
However, while ORC binding is required for replication licensing, ORC also binds to regions where initiation does not take place.
Muchardt, C. et al. Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α.
MLL2 binding is required for changes in chromosome architecture around developmental genes and establishes promoter-enhancer looping interactions in a cell-cycle-dependent manner.
From this preliminary SAR studies, it was speculated that the D-Ala-D-Ala binding was required for this series of compounds since the corresponding des-leucine derivative is inactive.
