Sentence examples for binding are not conserved from inspiring English sources
In fact, in all four UPF0201 proteins examined residues predicted to be involved in RNA binding are not conserved.
It has been demonstrated that the amino acid residues involved in DNA binding are not conserved between AP2 and ERFs [ 11, 12].
Sequence alignments with homologues and structural comparisons with CysK, a cysteine synthase that does not utilize a sulfur carrier protein, revealed high conservation of active site residues; however, residues in CysM responsible for CysO binding are not conserved.
The N-terminal Ig like domains of ROBO1 and ROBO4 are 42% identical but the residues identified for SLIT2 binding are not conserved in ROBO4 and are replaced by residues that are not compatible with binding of SLIT2.
In addition, molecular models based on the 3D structures of the HRM of B1/secretin-like GPCR of the GLP receptor group show that features crucial for ligand binding are not conserved in aGPCR, although hormone binding to secretin-type HRM might differ.
Nevertheless, the identification of numerous species-specific responses, evidence of divergent gene expression responses between species, and the discovery of distinct putative primary response sets in each cell line provides further compelling evidence that the effects of TCDD post-AhR binding are not conserved between species.
Some positively charged or polar residues that have been previously identified as critical for lipid binding in this ligand-binding triangle are not conserved in APPL1 (Supplementary Figures 1 and 3), consistent with the fact that APPL1 alone lacks membrane binding ability.
The surface areas involved in globotriose and glycan binding, respectively, are not conserved in PDLPs, but the structural similarity of plant DUF26 domains with different eukaryotic lectins could suggest a common evolutionary origin and a role as carbohydrate recognition modules45.
The metal binding residues are not conserved.
Neutralizing epitopes in the HA1 receptor binding site are not conserved between subtypes [24].
