Sentence examples for binding are necessary for from inspiring English sources
7. Oxidation of the enzyme (Fe2+ → Fe3+ transition) is influenced by Ca2+ ions [ 25]. 8. Endogenously generated 5-HP is the preferential substrate for the 5-LO mediated LTA-synthase reaction [ 26]. 9. ATP and membrane binding are necessary for 5-LO activation [ 13].
The characterization of SOX9 dimerization mutants identified in some CD patients, suggests that SOX9 binds to an inverted repeat of the heptameric sequence and that this dimeric binding is necessary for the SOX9-dependent expression of chondrocyte-related genes [13].
These results demonstrate that Mad3p binding is necessary for Cdc20 turnover, and suggest the intriguing possibility that the N-terminal Mad3 KEN box acts in trans as a Cdc20p destruction signal during early mitosis.
Nested deletions and site-specific point mutations of the CRE located at nucleotide −224 resulted in a significant loss of induction by cAMP, demonstrating that CREB binding is necessary for the stimulation of the gene [13].
If DNA binding were necessary for PARP-dependent mADPR accumulation, the PARP-dZF1 mutant, which has little or no detectable DNA binding capacity, would be expected to show little or no ability to reconstitute O/N stress-induced NAD degradation or TRPM2 activation in the DT40 system.
In turn, this binding is necessary for the subsequent recruitment of FANCD2, which allows the DNA repair process to initiate.
Receptor binding is necessary for the radiotracer to selectively localize in the targeted organ or tissue (e.g., tumor).
