Sentence examples for binding are essential to from inspiring English sources

Moreover, they provide evidence that phosphorylation changes induced by cofactor binding are essential to the ability of Gro/TLE1 to inhibit neuronal differentiation.

The crystal structure of ligand-free E. coli glutaminyl-tRNA synthetase (GlnRS) at 2.4 Å resolution shows that substrate binding is essential to construction of a catalytically proficient active site.

Thus our data suggests that in order for NOX5 EF1 to adopt an optimal conformation for Ca2+ binding, the structural change on EF2 upon Ca2+ binding is essential to increase its sensitivity.

If ICAM-2/α-actinin binding were essential to the observed ICAM-2-mediated redistribution of actin fibers, expression of ICAM2ΔCD would have no effect on actin fiber distribution and, similar to SK-N-ASpIRESneo cells, actin fibers in SK-N-ASpIRES.ICAM2ΔCD cells would be in a transverse configuration.

A kinetics study on VEGF-bevacizumab binding is essential to elucidate the fundamental mechanism of bevacizumab inhibition to the VEGF VEGFR angiogenic switch.

Continued international discussions leading to binding treaties are essential to reconcile the opposing needs".

It is well established that changes in actin organization and the levels of its binding proteins are essential to the cancer cell phenotype (reviewed in [ 27, 28]).

The single-domain binding events are essential to prevent the system from becoming stuck in an all PPDK1 or all PPDK2 state.

This surprisingly reveals that transcription factor binding sites are essential to explain the unmethylated state of the majority of CpG islands.

These enhancer regions seem to contain transcription factor binding sites which are essential to maintain SOX9 expression during development.

The results show that both the N-terminal integrin and C-terminal actin-binding functions of talin are essential to cell spreading and FA assembly.