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Residues from the core domain involved in RNA binding are coloured in purple, residues from the zinc finger in dark blue, and positively charged residues identified in RSV are shown in light blue.
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The three substrate binding tryptophan residues of C. fini are coloured in cian and the corresponding residues, W249, W286 and D304 of Streptomyces sp. GH12 in magenta.
The core domain is shown in purple cartoon representation, and RNA binding residues previously identified by NMR are coloured in brown with side chains shown in sticks.
SaTRIC protomers are coloured as in a, and CpTRIC protomers are coloured in grey.
Insulators and metals are coloured in red and blue, respectively.
Sequence tracts from S4-S5 to S5 are coloured in blue, S6 in pink, P helices are coloured in magenta.
Ghost nodes are coloured in green.
The base of the parallelepiped is coloured in blue and the lines projected in height are coloured in green.
The N-linked glycans are coloured in green.
The genes selected as query genes are coloured in red.
Carbon atoms in Pol α are coloured white, whereas in Pol δ are coloured in light brown.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com