Ai Feedback
Exact(6)
The effect of LPS on binding and unfolding of ColE3 may be indicative of a broader role of LPS for transport of colicins in general.
The second event is a composite of UP1 quadruplex recognition binding and unfolding of the G-quadruplex.
Until now, there has been limited information regarding the energetic forces that characterize the binding and unfolding of the telomeric G-quadruplex by UP1.
The results presented here represent the first examination of the energetic characteristics of the binding and unfolding of G-quadruplex DNA by UP1.
This idea is supported by a recently published report that makes a similar observation for the binding and unfolding of the K+ conformation.
We have found the binding and unfolding of the Tel-22 G-quadruplex structure by UP1 to be influenced by both the structure and stability of the deoxyoligonucleotide.
Similar(54)
The complex shape that is observed for the complete binding isotherm results from the heat change being the sum of the three enthalpy changes composed of the binding of 2 mol of UP1 and unfolding of the G-quadruplex structure.
Atomic force microscopy (AFM) experiments and steered molecular dynamics (SMD) simulations have revealed much about the dynamics of protein-ligand binding and unbinding, as well as the stretching and unfolding of proteins.
Thus, our data indicate that PA is stabilized throughout most of the protein by receptor binding, and the unfolding of these residues, despite being located in different domains, occurs at concomitant Gdn-HCl concentrations.
Apparently, substrate recognition, binding and unfolding lie on the chaperone partner, namely ClpC1/2 and ClpD.
One of the first indications that talin may be mechanically sensitive came from studies looking at talin:vinculin complexes 25 and the discovery that the vinculin-binding sites (VBS) in talin, each defined by hydrophobic residues on a single helix, reside within the interior of the folded talin rod domains, suggesting vinculin binding requires unfolding of talin domains to expose these VBS.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com