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Peptides MA11 and MA22 exhibited strong binding and transfer of 32P only to the three colon adenocarcinoma lines (Caco2, HCT116, and HCT15) and not to cervical (HeLa), fibrosarcoma (1080), pancreatic or lung adenocarcinoma cells.
In addition, COG1634 and TPK family members share the metal (Mg II)) ion-binding site, involved in binding and transfer of the diphosphate group (Supplemental Figures 1 and 2).
We attribute this decrease to an adverse steric effect caused by the incorporation of a quencher at the C-8 position of guanine on binding and transfer of the fluorophore moiety to the protein tag.
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Structural analysis of channels proposed that the conformational changes might have originated from the active site upon ligand binding and transferred to the rest of the protein via SRSs, which could thereby regulate the channels in CYP4A22.
(48) Parallels between IsdB-N2 and Shp reveal that abolishing a heme-iron ligand can have highly variable effects on the heme binding and transfer characteristics of the protein.
The novel architecture of GLTP markedly contrasts the conformational motifs of other lipid binding and transfer proteins which generally are dominated by β-sheet, i.e. β-grooves/concave cups and β-barrels, or helical bundles stabilized by multiple disulfide-bridges, i.e. saposin-folds.
In contrast, the MCF-Exo contains higher levels of nucleic acid, protein binding, and transfer proteins.
Intact alginate layers inhibited surface binding and electron transfer of solution phase ferricyanide based on anionic repulsion.
This process involves the binding of the X. laevis SNBPs and transfer of H2A-H2B thethe sperm chromatin [ 10].
Heparin binds to lipopolysaccharide-binding protein, and this binding facilitates the transfer of lipopolysaccharide to the CD14 receptor, thereby augmenting the endotoxin-induced activation of monocytes [ 9, 18].
This agrees with the hypothesis that the FMN-binding domain of reductase provides a major surface for the electrostatic interaction with aromatase, since electrons exit from the FMN-binding domain and transfer to the heme of aromatase.
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