Sentence examples for binding and the structure from inspiring English sources

DOSY was used to indirectly verify covalent binding and the structure of the product was further elucidated using NMR spectroscopy.

The I59A and A193S mutations have also been shown to abolish APY binding, and the structure shows that both of these EphA4 residues also participate in hydrophobic interactions with the peptide (Supporting Information Figure 1).

These nucleic acid analogues form methylene bridges after binding and lock the structure on the target DNA.

It is mentioned that MutL can dimerize upon ATP binding and that the structure of the complex would sterically allow MutL dimerization based on a previously published structure of the N-terminal domain bound to nucleotide.

Furthermore, molecular docking and 3D QSAR study by means of DS 3.5 (Discovery Studio 3.5, Accelrys, Co. Ltd) explored the binding modes and the structure and activity relationship (SAR) of these derivatives.

The finding of a pheromone binding protein and the structure of the replication module suggested that pLG2 is a pheromone responding plasmid.

In combination with computer modeling, the binding characteristics and the structure requirement for flavone and isoflavone phytoestrogens to inhibit human aromatase were obtained.

The sequences of bases in a system of strands thus determine the pattern of binding and the overall structure in an easily controllable way.

PXR activity is mainly regulated by direct ligand binding (and the unique structure of PXR allows many drugs and drug leads to bind to it), although it can also be regulated by various cell signaling pathways.

As mentioned in our response to point seven, we observed specific NAD and ADP binding in the structure and their effect on channel open probability (despite being less profound than Ca2+).

Mutations of Thr193 have been shown to remove PKG's cGMP-binding selectivity, and the structures presented here are consistent with these results [5].