Sentence examples for binding and the effect from inspiring English sources

These clones have been studied with regard to their isozyme specificity, biochemical modulation of binding and the effect of their binding on the enzyme activity.

Cells were used to determine the specifity of COX-2 antibody binding and the effect of stimulation on COX-2 expression.

In agreement with XPS spectra (data not shown), oxygen and nitrogen atoms significantly contributed to BDE-209 binding, and the effect of carbon atoms appeared to be less important.

Although ChIP-on-chip experiments and sequence-based methods have the ability to detect such putative protein-DNA binding sites, these techniques do not allow inference of directional transcriptional dependencies between DNA binding and the effect on regulation of gene expression.

Our lab has previously investigated the binding thermodynamics and conformation of CaM Fas DD complexes using explicit solvent molecular dynamics simulations and implicit solvent binding free energy calculations, presenting structural evidence of CaM Fas DD binding and the effect of the Fas DD V254N mutation on CaM Fas DD interaction.

Modern protocols that involve molecular dynamics simulation can address key issues such as the free energy of binding (affinity), ligand-induced GPCR flexibility, ligand binding kinetics, conserved water positions and their role in ligand binding and the effects of mutations.

A complete and conclusive understanding of aromatase inhibition has remained elusive because of limited understanding of conformational changes of aromatase upon ligand binding and the effects of interactions with the active site and the heme iron on ligand affinities [26 28].

An additional possibility for the low correspondence between TF binding and the effects of TF deletion is false negatives.

The differences in binding and the effects on receptor function may explain the differences in the clinical effects between palonosetron and the first-generation 5-HT3 receptor antagonists.

In order to optimize cell labeling, the incubation conditions of 1– 4 and Prohance in HeLa cells were determined by quantifying toxicity, nonspecific binding, and the effects of cholate and incubation time on cell labeling.

Because it is unlikely that the l-aspartate binding site is in the MgATP binding site, the acetyl-CoA binding site, or the MgTNP-ATP binding site, the effects of l-aspartate on acetyl-CoA activation, MgTNP-ATP activation, and MgATP binding and the effects on biotin carboxylation and/or carboxybiotin translocation are allosteric, induced from a remote l-aspartate binding site.