Sentence examples for binding and the design from inspiring English sources

In addition, the mechanism of organophosphorus binding and the design of effective reactivators are reviewed.

In this picture the dimensionality of receptor space is determined by molecular principles involving the number of ligands of interest, their relevant concentrations, the energetics of ligand binding, and the design limitations of protein structures.

In order to avoid an impact on target binding and biodistribution, the design of a dual-modality imaging agent should ideally aim for the incorporation of a fluorochrome as well as radionuclide with a small "footprint".

This finding has implications for the mechanism of binding and for the design of misonidazole analogues which might be used to identify hypoxic zones in tumours.

The molecular recognition among cytosines, and the molecular heterosynthons of molecular salts fabricated through proton-transfer reactions, might be used to investigate the theoretical sites of cytosine-specific DNA-binding proteins and the design for molecular imprint.

Specific binding involves the design and synthesis of receptors that is non trivial.

Identifying the binding sites for drug molecules on HSA can aid in determining the structure activity relationship of albumin binding and assist in the design of molecules with altered albumin binding.

Recent advances in this area include the design of cavities within helix bundles for the binding of anesthetics, the design of β-hairpins for the recognition of nucleotides and oligonucleotides, the redesign of protein binding sites for unique ligands, and the design of mini-proteins via protein grafting for the recognition of proteins and DNA.

Key insights into the structure activity relationship derived from the CoMFA analysis concur with experimentally observed data, thus the CoMFA models presented here find utility for predicting the binding affinity, and guiding the design, of novel SNC80 analogs and related δ opioid receptor agonists.

Combining the two models for column pressure and for dynamic binding capacity allows the design of preparative scale columns that maximize productivity while meeting specified pressure constraints.

Further defining the physical interfaces of Gas1-Shh and Gas1-Ret binding should allow the design of function distinguishing mutations of Gas1.