Sentence examples for binding and the ability from inspiring English sources

A number of anti-VEGF human single chain variable fragments (scFv) were screened for several characteristics such as a competition with 2C3 for binding to VEGF, the ability to block VEGF∶VEGFR2 binding, and the ability of the scFv to bind to different VEGF isoforms such as VEGF165 and VEGF121.

The EGFR status of the two cell lines was confirmed by measuring 125I]iodoEGF binding, and the ability of MNT and 125I]SGMIB-MNT to bind specifically to EGFR was documented as previously described [7] prior to the initiation of any of the other experiments.

Both CRM1 binding and the ability to direct nuclear export were affected by mutation of these phosphorylation sites; thus, we propose that Cyclin B1 phosphorylation at the G2/M transition prevents its interaction with CRM1, thereby reducing nuclear export and facilitating nuclear accumulation.

The important properties of magnetic particles for biological and biomedical applications are controllable shape (for biological and biomedical purposes, they must have spherical shape), biocompatibility, nontoxicity, narrow and moderate size distribution, high crystallinity, large surface areas (for maximal protein or enzyme binding), and the ability to well disperse in an aqueous medium [14 17].

However, with increasing water solubility, other biological properties such as receptor binding and the ability to cross the cell membrane were blunted.

Several such sites in mRNA form a cluster and increase the probability of binding and the ability to inhibit protein synthesis.

These results were puzzling, considering the ability of Abf1 and Rap1 bindings sites to establish silencing at HMR-E in the absence of an ORC binding site, and the ability of multiple Rap1 sites to nucleate telomeric silencing (Brand et al. 1987; Cockell et al. 1995; Hecht et al. 1996).

Together, these results support a model of activation of PhoB in which phosphorylation promotes dimerization via the α4-β5-α5 facenhances enhances DNA binding and thus the ability of PhoB to regulate transcription.

Ligands 7a,b and the corresponding conformationally constrained analogues 8a g were synthesized and their interactions with the 5-HT4 receptor were examined by measuring both binding affinity and the ability to promote or inhibit receptor G protein coupling.

In addition to the positive effect of the magnesium component, the high phosphate binding capacity and the ability to slow the possible mechanism of the vessel calcification process OsvaRen® therapy has a decisive influence on the overall costs associated with these therapeutic options.

We have also investigated the receptor binding affinity and the ability of these analogs to stimulate intracellular signaling pathways, although in our case by measuring phosphorylation of ERK1/2.