Sentence examples for binding and stimulation of from inspiring English sources

Our results clearly indicate an essential contribution of subdomain 2 in increasing the intrinsic ATPase activity as well as in mediating nucleic acid binding and stimulation of ATP hydrolysis, as seen in all known DEAD-box proteins.

Extracellular actions of S1P are mediated via binding and stimulation of five different G-coupled receptors, S1P1 5 [ 3].

This stands in contrast to the activating function of extended-C/EBPα that requires the NoLS for rDNA promoter binding and stimulation of rRNA synthesis.

Proteins with repeated amino acid motifs are implicated in antigenic diversity and recognition, host-cell receptor binding and stimulation of the host immune response [ 40].

Levels of functional GnRH-R in breast-derived cell lines were assessed using I-ligand binding and stimulation of H-inositol phosphate production.

On activation by ligands, NRs change their conformation, which in turn facilitates the recruitment of coactivators and dissociation of corepressors and enables DNA binding and stimulation of gene transcription.

Cadmium, a known carcinogen and risk factor for lung cancer [ 12, 13], accumulates in the human body with age [ 14, 15], and has several unique properties, including binding to and stimulation of the estrogen receptor alpha [ 16- 18]and inhibition of DNA repair [ 19- 22], which are potential risk factors for breast cancer carcinogenesis.

Interestingly, GRSF1 is a gene that is involved in RNA binding and also stimulation of translation of viral mRNAs in vitro.

In both settings, oxytocin exerts its effects via binding to oxytocin receptors and stimulation of intracellular signaling.

Functions of SAA relating to tumourigenesis (Malle et al, 2009) include binding to extracellular matrix components with subsequent potential modification of cell binding, enhancement of plasminogen activation and stimulation of matrix metalloproteinase (MMP) production, reported in several cell types including renal cancer cell lines (Paret et al, 2010).

The established understanding of fibrogenesis by TGF-β signaling is initiated by the activation of Smad-mediated pathway upon ligand binding, followed by myofibroblast transformation and stimulation of the synthesis of extracellular matrix (ECM) proteins [ 23].