Sentence examples for binding and stabilization of from inspiring English sources
In hypoxia, proline hydroxylation is inhibited resulting in decreased VHL binding and stabilization of protein.
Therefore, Arg140 from the lid domain participates in substrate binding and stabilization of the reaction intermediate and plays a key role in the phosphotransfer apart from Lys 14 from the P-loop.
Since the uncharged alanine cannot compensate for the charge stabilization during phosphoryl transfer, these results are consistent with a role for the positive charge of Arg140 in ATP binding and stabilization of the phosphoryl intermediate during catalysis.
Our findings support previous data showing that serum IgE is associated with an upregulation of FcεRI as a consequence of IgE binding and stabilization of the receptor complex on the cell surface [4], [5], [6].
The importance of a strictly maintained intracellular environment, particularly at higher concentrations of copper, is underscored by the strong up-regulation and abundance of proteins having annotated functions for the binding and stabilization of nucleic acids and proteins and presumptive metabolic flux towards production of reductants, potent antioxidants, and protectant metabolites.
It ensures minus-end binding and stabilization of microtubules on the centrosome area that faces chromosomes.
Several amino acids demonstrated to be hallmarks of functional eIF4E proteins are lacking, including amino acids involved in cap-binding and stabilization of the protein structure [56].
Testosterone and DHT both bind to AR, but DHT is more active, displaying greater binding affinity and stabilization of the AR complex [ 23].
The mitochondrial localization determines the binding with and stabilization of ferredoxin reductase (Fdxr), a flavoprotein transactivated by p53.
Post-translational modifications of this isoform, AUF1 p40, are altered concomitant with changes in RNA binding activity and stabilization of ARE-containing mRNAs in phorbol ester-treated monocytic leukemia cells [ 32].
Hsp90s/HSPCs are required for the degradation, regulation, ligand-binding affinity and stabilization of the androgen receptor, as well as for its trafficking (Peterson and Blagg, 2009).
