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The topo II inhibition exerted by dexrazoxane is due to its binding and stabilisation of the protein/DNA complex.
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In this model, exact sequences would have been less important than general attributes such as positive charge (thereby permitting binding to and stabilisation of existing ribozymes or functional RNAs).
HSP90 is a potential BCAS2-binding protein from proteomic assay (Chen et al, 2013) and an essential molecular chaperone for the correct folding and stabilisation of AR (Vanaja et al, 2002; Centenera et al, 2013).
Conservative treatment including blood transfusions achieved clinical improvement and stabilisation of the haematocrit.
In both cases, we are effectively able to control further growth and stabilisation of the nanoparticles.
At this main dumpsite, compaction and stabilisation of the ash was undertaken.
Nanotechnology deals with the synthesis and stabilisation of various nanoparticles [3].
Bio-emulsifiers are essential in the formation and stabilisation of emulsion.
Thirty patients (46.9%) experienced stabilisation of disease, with a rate of overall clinical benefit (complete responses, partial responses, and stabilisation of disease) of 85.9%.
These findings suggest a role for SYCP3 in chromosome compaction and stabilisation of the cohesin core.
Another treatment option for the control of symptoms and stabilisation of the tumour is radionuclide therapy.
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