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Zoll, S. et al. Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate peptide complex structures.
The glycan receptor binding and specificity of influenza A viral hemagglutinin (HA) are critical for virus infection and transmission in humans.
Direct binding and inhibition enzyme immunoassays were carried out to evaluate binding and specificity of anti-glycated-DNA autoantibodies (anti-DNA-AGE autoantibodies) in sera of diabetes patients.
This study provides the molecular bases for recognition, binding and specificity of peptide transporters for dipeptides with a charged amino acid residue at the N-terminal position.
In summary, the crystal structure of YePEPT together with structure-function studies have provided the molecular bases for the recognition, binding and specificity of charged amino acid residues at the N-terminal position of dipeptides by peptide transporters of the POT family.
The X-ray crystal structure of the peptide transporter YePEPT from the bacterium Yersinia enterocolitica together with functional studies have unveiled the molecular bases for recognition, binding and specificity of dipeptides with a charged amino acid residue at the N-terminal position.
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In vitro CD13 receptor binding affinity and specificity of 99mTc-NGR were assessed via competitive cell binding assay.
Triad Therapeutics' proprietary technologies enable dramatic increases in both the speed of lead compound generation and the quality (binding affinity and specificity) of the compounds produced.
Exposure of pep14 to a synthetic mixture comprising hIgM, hIgG1 and bovine serum albumin had no adverse effect on the binding capacity and specificity of pep14.
The back mutation of these residues to the corresponding chicken residues completely recovered the pT231-peptide binding affinity and specificity of the humanized antibody.
This suggests that the binding ability and specificity of Pluronic-PEI-DR5-TAT to DR5 reduces toxicity in normal cells.
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