Sentence examples for binding and reduction of from inspiring English sources

However, because PEGylation may also have unfavourable effects, such as inhibition of receptor binding and reduction of target-to-background ratio, its impact must be carefully evaluated for a new peptide.

AF therefore inhibits TR with a dual mechanism, i.e. by blocking both binding and reduction of oxidized trypanothione by TR.

Aβ can serve as a metalloenzyme to catalyze the generation of neurotoxic H2O2 from O2 through binding and reduction of Cu (II) [ 35].

The temperature was 37 °C in the case of the measurements involving substrate and product binding and reduction of ferric P450 4A11.

In this subsection we describe the trapping and EPR/ENDOR characterization of the E4 intermediate as activated by the accumulation of four [e /H+] for binding and reduction of N2.

The first 40 years of study of purified nitrogenase did not see the definitive characterization of any intermediates associated with the binding and reduction of N2, leaving the identity of the reaction pathway unresolved.

Tolerance and detoxification mechanisms often involve extrusion of the toxic ions from the cell, sequestration within internal organelles, chelation by metal-binding proteins, and reduction of uptake.

A better understanding of the biosorbent mechanisms responsible for Pt(IV) binding and reduction could contribute to the development of a method for fabrication of platinum nanoscale devices, and for an improvement of preparation of highly dispersive supported platinum catalysts by biotechnological methods.

DHCR24 contains a highly conserved FAD (flavin adenine dinucleotide -binding dinucleotide -bindingedomainn of desmosterol to cholesterol is dependent on FAD [ 7], suggesting functionality of the conserved domain.

Namely, R173 was suggested to be involved in substrate binding and reduction as well as in stabilization of the transient intermediate hypochlorous acid (reaction 1).

The MoFe protein contains two metalloclusters: FeMo-co, a [Mo-7Fe-9S-C-homocitrate] cluster which serves as the active site of substrate binding and reduction and the P-cluster, a [8Fe-7S] cluster which shuttles electrons to FeMo-co [ 2, 3].