Sentence examples for binding and rapamycin interaction from inspiring English sources

In addition, the FRB domain contains several residues necessary for both phosphatidic acid binding and rapamycin interaction [ 74, 75].

The binding of FKBP12 and rapamycin to mTOR (mammalian target of rapamycin) inhibits its role in regulating cell growth and cancer progression [ 2].

The binding of FK506 and Rapamycin to a common intracellular protein was originally demonstrated in Jurkat T cells, which were rendered resistant to FK506 mediated blockade of IL2 induction when pretreated with Rapamycin (Bierer et al., 1990).

The binding of FK506 and Rapamycin to a common intracellular protein was originally demonstrated in Jurkat T cells, which were rendered resistant to FK506 mediated blockade of IL2 induction when pretreated with Rapamycin [13].

FK506 binding protein 12 is a major binding partner for FK506 and rapamycin (Siekierka et al, 1989).

Rapamycin leads to the formation of a ternary complex by binding simultaneously to the FRB [FKP12 and Rapamycin Binding] domain of TOR and to the ScFKBP12 protein [ 14].

The peptide prolyl isomerase FKBP12 (FK506-binding protein 12) was initially characterized for its role in binding the immunosuppressants FK506 and rapamycin.

The immunophilin FKBP12 (FK506-binding protein of 12 kDa) was first characterized for its role in binding the immunosuppressants FK506 and rapamycin.

HEAT domain can mediate protein-protein interactions and FRB domain is a conserved 11 kDa region necessary for the binding of rapamycin and regulatory-associated protein of mTOR (RAPTOR) [ 4].

Renda, M. et al. Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci.

There were no differences between control and rapamycin treated subjects and no interaction effect on the glucose AUC.