Sentence examples for binding and protein dimerization from inspiring English sources

Both aberrant transcripts maintain the RUNX1 open reading frame, but result in the loss of the RUNT domain, which is critical for DNA binding and protein dimerization.

Examples include proteins involved in disulfide bonding, GTP binding and protein dimerization.

Starting at the N-terminal end of the gene, the 'M' or MADS domain is highly conserved across eukaryotes, and mediates DNA binding and protein dimerization [ 14, 15].

In previous studies examining inter-specific and intra-specific variability in AHR sequences [ 45, 65, 68], the most highly conserved region is the basic-helix-loop-helix (bHLH) domain, which is involved in DNA binding and protein dimerization [ 69, 70].

The basic helix loop helix/Per Arnt Sim domain is highly conserved among the SRC members, and it serves as a DNA binding and protein dimerization motif in many transcription factors [ 11].

NF-κB subunits are sensitive to small variations in the κB sites because the RHR region of NF-κB, which is responsible for both DNA binding and protein dimerization, is bimodular (including the N-terminal domain and C-terminal dimerization domain) and connected through a small linker peptide.

All of the functionally enriched GO terms identified thus far for those genes up-regulated at 24 and 48 hrs p.i. appeared to be closely involved in either genomic transcription (i.e., TFs, sequence-specific DNA and/or double-stranded RNA binding, oligopeptide transporter, and protein dimerization) or inflammatory responses (Figure 4A).

In the present paper, we review the progress made over the last decade to elucidate the structural mechanisms involved in modulation of DNA binding and protein partner selection during dimerization.

DNA binding, protein dimerization, and transcription coactivator activity are important functional activities of bHLH domains.

If an inhibitor does not negate hypoxic induction of HIF-1 α protein, the other mechanisms (DNA binding, protein dimerization, or transcriptional activity) should be considered for further investigation.

The MH4 motif corresponds to the homeodomain, which is known to be involved in DNA binding and protein-protein (homo- or hetero-) dimerization.