Within the active site are a number of conserved residues that are important for SAM binding, catalysis, and maintaining the overall architecture of the PRMT1 active site.
Natural selection might promote heterodimers via the increase of the combinatory potential of the OBP (increasing either the spectrum of possible target odorants or the binding-specificity) and maintaining, therefore, the co-localization of different OBPs in the same cells.
Among them, tartaric acid derivative (5) exhibited the most effective reduction of nonspecific binding proteins, whilst maintaining binding of the target protein.
We also observed the maintaining of the binding of SATB1 to these MARs, that is possibly important for inter-MAR association and the reactivation of genes transcription in next cell cycle.
Albumin is the most abundant plasma protein with multifunctional properties such as ligand-binding and transport, maintaining the colloid osmotic pressure of plasma, and regulating neutrophil function [1].
At the same time, individual nations and power blocs, such as the EU, need to announce their own binding carbon cut commitments and maintain the momentum of the Copenhagen talks.
Thus, they indirectly facilitated a shift in research focus toward the potential role of enzymes and specific binding proteins in maintaining the composition of retinoid isomers in vivo.
We also describe our continuous efforts in achieving a label-free detection without non-specific binding while maintaining the activity and stability of immobilized biomolecules.
She said her mother was the binding force that held her family together through tragedy and maintained a sense of normalcy.
Recently, we have reported that asymmetric Fc engineering, which introduces different substitutions into each Fc region of heavy chain, can further improve the FcγR binding while maintaining the thermal stability of the CH2 domain by fine-tuning the asymmetric interface between the Fc domain and FcγR.
