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Fig. 4 Membrane binding and internalisation of 68Ga-PSMA-HBED-CC after 5 h of incubation in androgen-sensitive (revCRPC), castration-resistant prostate cancer cells (CRPC) and abiraterone-insensitive cells (CRPCAA) as well as in revCRPC after 48 h ADT with testosterone (T) withdrawal and 5 μM abiraterone acetate (AA).
Trypanosomes rely on binding and internalisation of circulating plasma haptoglobin-haemoglobin (Hpr-Hb) to acquire iron necessary for their survival.
Yersinia invasin, Listeria internalins and Streptococci LrrG protein are surface proteins that play key roles in binding and internalisation of these bacteria in their mammalian hosts [ 12, 13].
Clathrin-coated pits are essential for the binding and internalisation of hemoglobin by pinocytosis [ 72]. *Accession number represents transcripts derived from this analysis and submitted to Genbank.
It might be that binding and internalisation of EPHA2 alone is not sufficient to affect OS cell survival and that additional stimuli are needed.
Thus, by using these three cell lines, we included all necessary controls for the in vitro and in vivo evaluation and our cell uptake studies demonstrated receptor selective binding and internalisation of [F]FProp-C*RRETAWAC*-OH only for the DU145, therefore nicely confirming the receptor binding studies on isolated purified integrins.
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Bacteria can also induce Ca2+ responses that play a role in the cytoskeletal rearrangements required for cell binding and for internalisation of the microorganism [14].
Bacteria can induce Ca2+ responses that play a role in cytoskeletal rearrangements required for cell binding and for internalisation of the microorganism [14].
Bacteria can induce Ca2+ responses that play a role in the cytoskeletal rearrangements required for cell binding and for internalisation of the microorganism [14].
[68Ga(THP-TATE)] was rapidly internalised into SSTR2-positive cells, but not SSTR2-negative cells, and receptor binding and internalisation were specific.
125I-GH binding and internalisation was performed as previously described [15].
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binding and activation of
binding and transport of
binding and dissociation of
binding and selectivity of
binding and accumulation of
binding and invoking of
binding and discovery of
binding and hemolysis of
binding and hybridization of
binding and enactment of
binding and uptake of
binding and migration of
binding and releasing of
binding and recognition of
binding and mechanism of
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