Sentence examples for binding and interactions with from inspiring English sources
Dynamic associations between APPL proteins and cell membranes are likely to be coordinately regulated by BAR domain-mediated dimerization, phosphoinositide binding, and interactions with protein binding partners, including transmembrane receptors, signaling proteins, and GTP-bound RAB5.
It is interesting to note that all three segment exchanges occur on the surface of the protein which is important for substrate binding and interactions with ligands.
Like their vertebrate counterparts, these fly proteins contain an approximately 300-amino acid long, multifunctional and conserved Rel homology domain, which mediates dimerization, DNA binding, and interactions with IκB inhibitor proteins [ 7- 9].
The diversity in the types of gene regulation carried out by PPARβ/δ is consistent with dynamic binding and interactions with chromatin and indicates the presence of complex regulatory networks in cells expressing high levels of this nuclear receptor such as keratinocytes.
However, in addition to the intrinsic thermostability conferred by its amino acid sequence, additional stabilizing factors such as ligand binding and interactions with salts and/or organic compounds such as glycerol and sucrose must help BsDHFR achieve the necessary stability in vivo to function at temperatures above 70 °C.
The third gene, dax1, is a member of the nuclear receptors superfamily, with a ligand-binding domain at the C-terminal and LxxLL motifs, which enable the binding and interaction with potential targets (reviewed in [45]).
These findings show that lack of ASM results in anomalous membrane binding and interaction with syntaxin1 of Munc18 at advanced stages of the disease when the docking alterations are evident.
The Medicago gene has 40% identity and 58% similarity to the A. thaliana protein and also contains both of the conserved domains that were shown to function in binding and interaction with other proteins, namely the BTB/POZ and ankyrin repeats domains [49].
Therefore, among the major functions of these unstructured, intrinsically disordered proteins are nucleic acid binding, metal ion binding, heme binding and interaction with membrane bilayers [ 37].
Targeting of SCML2A to chromatin involves the coordinated action of the MBT domains, RNA binding, and interaction with PRC1 through the SPM domain.
