Sentence examples for binding and induction of from inspiring English sources

Leukotriene binding and induction of internalization were furthermore tested using homologous competition binding and antibody-feeding experiments respectively.

Collectively, these results confirm the role of the C-terminal region (aa 128 165) of the M1 protein in Hsp70 binding and induction of apoptosis.

DOI: http://dx.doi.org/10.7554/eLife.00499.023 10.7554/eLiFigure99.024 figure 4—figure supplement 2. -DR103 effectively competes with DHT for AR binding and induction of AR-regulated luciferase.

Those results stand in accordance with the observations made for lprcg mice, carrying spontaneous CD95 mutation (I225N) that prevents both FADD binding and induction of apoptosis.

Second, TCDD may impair RAR functioning as it inhibits both atRA binding and induction of target genes in cultured cells (Lorick et al. 1998; Weston et al. 1995).

This last compound was one of the first examples of drugs capable of restoring wt p53 conformation, thereby allowing sequence-specific DNA binding and induction of p53 target genes (149).

These proteins are able to regulate iron efflux and consequently iron absorption, because overexpression of ferroportin1 is induced by cellular Fe and is suppressed by hepcidin, which inhibits Fe efflux through binding to and induction of the degradation of ferroportin1 [ 3, 6].

In this respect, we have previously demonstrated that TGFBI-derived proteolytic peptides provoke cell death through binding to αvβ3 integrins and induction of caspase 3 activation (Irigoyen et al, 2010).

For our own data, we chose to define threshold values for binding and induction that maximize the fraction of genes that are both bound and induced, above and beyond the number that is expected by chance.

To define a set of genes that are both bound and induced, we determined threshold p-values for binding and induction that maximized the fraction of genes that meet both criteria, above and beyond the number expected by chance (see Methods).

Like Ras proteins, these Rho proteins are activated via extracellular signals that cause binding and hydrolysis of GTP and induction of downstream effector molecules [22].