Sentence examples for binding and hydrolysis of from inspiring English sources

Four domains of G1, G3, G4 and G5 participate in the binding and hydrolysis of nucleotides.

These rearrangements couple the binding and hydrolysis of ATP to an overall reaction cycle in which substrate proteins are bound, encapsulated and released.

However, the mutation W187H could facilitate the relocation of Asp287, while D287A directly eliminates the hindrance of Asp287, both of which offer sufficient space for the binding and hydrolysis of substrate.

Although the transport process takes place in the TMDs, which provide the substrate translocation pathway across the cell membrane and control its accessibility between the two sides of the membrane, the energy required for the process is provided by conformational changes induced in the NBDs by binding and hydrolysis of ATP.

To maintain high specificity and allow probe binding and hydrolysis of a probe with low melting temperature, a two-stage touchdown PCR was designed with a first round of amplification at high temperature and a subsequent round at low temperature to allow accumulation of fluorescence.

Thus, it appears that the residue corresponding to Phe288 affects both the binding and hydrolysis of substrate.

Further biochemical analyses of this naturally occurring mutation revealed the central role of GTP binding and hydrolysis for the antiviral mechanism of MxA.

These motifs are involved in ATP-binding and hydrolysis of the β-γ phosphate diester bond [19] leading to specific conformational changes.

Similar to the effects of compromising mutations in the SLIDE domain of ISW2 on repositioning efficiency and directionality of nucleosome translocation, the ATP binding and hydrolysis cycle of ISWI may contribute to the random walk behavior that we observe.

It is again important to note here that the nucleotide binding and hydrolysis pocket of ring helicases is formed at the interface of subunits (see 32, for a review).

At its core, Hsp70 chaperone activity is characterized by a cyclic bind and release interaction with client proteins, which is regulated by the ATP binding and hydrolysis activity of the NBD.