Sentence examples for binding and histone modification from inspiring English sources

Both TF binding and histone modification are predictive of gene expression levels [26].

When transcription factor binding and histone modification levels are mapped in the same state (cell line, condition) they appear highly correlated.

Furthermore, we validated the credibility of the identified erythroid-specific KLF enhancers through integrated bioinformatic and biochemical approaches to determine sequence conservation, TF binding, and histone modification markers.

Unraveling transcriptional regulatory networks is a central problem in molecular biology and, in this quest, chromatin immunoprecipitation and sequencing (ChIP-seq) technology has given us the unprecedented ability to identify sites of protein-DNA binding and histone modification genome wide.

Multiple transcription factor binding and histone modification tracks, including more than 50 different transcription factors and 11 different types of histone modifications in H1 hES cell line [ 33] are grouped as "Transcriptional Regulation".

Motivated by this unsolved question, a systematic study of associations between TF-DNA binding and histone modification in yeast was carried out by integrative analysis of diverse datasets [ 8, 9, 24- 27].

ChIP-Seq has become the method of choice for genome-wide characterization of transcription factor binding, polymerase binding, and histone modifications [ 2].

Compared with DNA methylation, aberrant DNA binding and histone modifications including acetylation and methylation may have had even more important roles in APL pathogenesis and treatment response.

In the last couple of years ChIP-Seq has become the method of choice for the genome-wide characterization of TF binding, as well as polymerase binding and histone modifications.

As a result of opposite CTCF cohesin binding and histone modifications, different long-range interactions are established in BWS and SRS and are likely to influence IGF2-H19 expressinn in a reciprocal manner.

For each method we used the default settings, although transcription factor binding and histone modifications can differ substantially in their properties (eg, length of the region) yet specifying the optimal parameters in an unbiased way is difficult.