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Conversely, in the example illustrated in Figure 2, the subject terms (protein binding and histone binding) are more complex than the object terms.
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Nekrasov, M., Wild, B. & Müller, J. Nucleosome binding and histone methyltransferase activity of Drosophila PRC2.
ChIP-Seq has become the method of choice for genome-wide characterization of transcription factor binding, polymerase binding, and histone modifications [ 2].
To further test the temporal relationship of CpG methylation, MeCP2 binding, and histone deacetylation, we analyzed MeCP2 binding and histone acetylation levels at the FAM204A ASE in HCT116-WT and HCT116-DKO cells.
In the last couple of years ChIP-Seq has become the method of choice for the genome-wide characterization of TF binding, as well as polymerase binding and histone modifications.
Gilbert, N. et al. DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction.
Examples include the regulation of transcription and linker histone binding.
For example, from this model, Nogales, Ciferri and their co-authors have localized the molecular structures of individual domains involved in histone binding and methylation.
Thus, DNA methylation is upstream of histone modification in this model of methyl-DNA binding proteins and histone modification.
The calculations establish the relationship between DNA sequence and histone octamer binding affinity.
Dimerization of chromodomains will juxtapose two histone binding sites and enable the chromodomains to bind two histone tails simultaneously.
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