Sentence examples for binding and heterodimerization of from inspiring English sources

TGFβ signaling occurs following ligand binding and heterodimerization of Type I and Type II TGFβ receptors.

Ligand binding stimulates homodimerization and heterodimerization of EGFR family members.

RUNX family genes share a region, the Runt domain, which, with its partner subunit core-binding factor beta (CBF β), is responsible for specific DNA binding and heterodimerization and activates or represses transcription through the recruitment of various coactivators and corepressors depending on the cellular context.

Neh1 contains the bZip DNA binding and heterodimerization domain through which Nrf2 forms a heterodimer with a small Maf transcription factor.

We show that COMMD1 competes with the chaperone heat shock protein HSP90β for binding to the NH2-terminal DNA-binding and heterodimerization domain of HIF-1α to regulate HIF-1α stability together with HSP70.

Each half transporter consists of a nucleotide binding domain and a membrane-spanning domain, and heterodimerization of PatA and PatB is required to form a functional transporter (5).

The binding of the ligand to the extracellular domain induces HER1 homodimerization and heterodimerization of the remaining receptors, especially HER2 [ 4, 5].

Klein, C. L. et al. Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.

Nevertheless, proteolytic cleavage of HER4 and heterodimerization of HER2/HER4 occurred and thus sustained HER2 phosphorylation.

The DBD also contributes to homo- and heterodimerization of nuclear receptors.

In fact, homo- and heterodimerization of cysLTRs and purinergic receptors have been widely suggested [ 15, 16].